Haematological and Hepatorenal Alterations Induced by Potash (Akanwu) on Male Wistar Rats

Introduction: Potash refers to the various naturally occurring water-soluble compounds of potassium used as a traditional food additive in Nigeria. Several health warnings have highlighted deleterious effect their consumption.
 Aim: The present study is aimed at evaluating effects graded doses potash consumption on haematological and hepatorenal indices using Wistar rat models.
 Materials Methods: was locally sourced elemental composition determined by X-Ray diffraction (XRD). Twenty (20) male rats (170 – 200g) were for divided into four (4) groups five (5) animals each. Group 1 served control while Groups 2 4 experimental group received an aqueous mixture via oral gavage 200, 400 800mg/kg respectively thirty (30) days.
 Results: XRD analysis revealed presence (27.44%), phosphorus (14.27%), antimony (5.18%), barium (4.27%), fluorine (2.78%), cadmium (2.06%), yttrium (1.63%), tellurium (1.32%), caesium (1.12%), niobium (1.04%), sodium (0.42%) germanium (0.06%). Results from parameters show significant reduction mean values red blood cell count, haemoglobin concentration packed volume among compared (p<0.05) significantly increased corpuscular volume, haemoglobin, white lymphocytes, neutrophils, MID percentage, aspartate aminotransferase, alanine alkaline phosphatase, urea, creatine, sodium, chloride ions (P<0.05).
 Conclusion: data presented has shown that chronic can negatively alter profiles rats. Therefore, this considers potash, possible toxicant blood, liver kidney.